Structure modeling of artificial bone tissue based on reverse engineering and UG secondary development

doi:10.16731/j.cnki.1671-3133.2018.03.028

Abstract

Abstract: In order to lessen complication and additional trauma from conventional repairing solution,autologous bone grafting,the preparation method of bioactive substitute is presented.The key of prosthesis technology is bioactive substitute can improve pathologic organ function and structure.Based on reverse engineering and UG secondary development,Mimics medical image software was used for bone shape by reverse modeling.Then import the model into UG,process entity,generate mesh,and simplify analysis.And then,the structural model of porous artificial bone tissue was calculated and gained by programming language.Finally,taking the structural model as the mould,according to the rapid prototyping theory,artificial prosthesis with biological activity was produced by the rapid prototyping machine.

Key words: prosthesis, artificial bone tissue, UG secondary development, reverse engineering

CLC Number:

TP39

Yu Tianbiao,Sun Xue,Ha Da. Structure modeling of artificial bone tissue based on reverse engineering and UG secondary development[J]. Modern Manufacturing Engineering, 2018, 450(3): 154-159.

References

[1] 胡永善.骨与肌肉疾病康复的现状与任务[J].中国康复医学杂志,2002,17(6):326-327.
[2] 张智凌.密质骨多级微结构的强韧机理[D].重庆:重庆大学,2014:1-7.
[3] 张志广.人工股骨假体多尺度建模及其生物力学研究[D].沈阳:东北大学,2011:16.
[4] 郑扬,李危石,刘忠军.骨组织3D打印:骨再生的未来[J].北京大学学报(医学版),2015,47(2):203-206.
[5] 曲爱丽.三种缺损状态的下颌骨假体的设计和生物力学评价及动物试验研究[D].上海:上海交通大学,2006:1-6.
[6] 李俊辉,俞兴,穆晓红,等.人工颈椎间盘不同涂层影响骨髓间充质干细胞的黏附及分化[J].中国组织工程研究,2014(12):1938-1943.
[7] DONG L,WU D,LIU N,et al.The Reconstruction of the Finite Element Model of Artificial Knee Joint Based on RE Technology.International Conference on Computer-Aided Industrial Design & Conceptual Design[C].New York:IEEE,2009:1370-1373.
[8] 张海峰,宋翠荣,赵文涛,等.髋关节外展角度对股骨颈应力分布的影响[J].生物医学工程学杂志,2016(2):274-278.
[9] 孟祥杰,葛世荣.基于逆向工程技术的人体股骨近端形态参数误差分析[J].中国组织工程研究与临床康复,2011,15(35):6471-6474.
[10] 陈若瀚,陈盛贵,四库.基于快速成型及逆向工程技术的脸部假体实验研究[J].东莞理工学院学报,2013,20(1):87-91.
[11] 田卫军,李郁.逆向工程与快速制造技术在人工假体上的应用[J].制造业自动化,2014(12):19-23.
[12] 杨硕.心脏模拟器的开发与输出流量特性的研究[D].沈阳:东北大学,2013:33-34.
[13] 哈达.人工骨组织仿生结构造型技术研究[D].沈阳:东北大学,2012:25-28.

[14] 殷国富,胡饶兵.UG NX4产品设计实例精解[M].北京:机械工业出版社,2007.
[15] 郝守海,徐茂林.基于UG/Grip的客车设计辅助程序组的开发.2010年中国客车学术年会论文集[C].西安:陕西科学技术出版社,2010:13-16.
[16] ZHANG J,NIE J,ZHANG Q,et al.Preparation and Characterization of Bionic Bone Structure Chitosan/Hydroxyapatite Scaffold for Bone Tissue Engineering[J].Journal of Biomaterials Science Polymer Edition,2014,25(1):61-74.
[17] YOUSEFI K,ZEBARJAD M,KHAKI V.Comparison of Polyethylene Glycol Effect on Hydroxyapatite Morphology Produced into Different Methods:Sol-gel and Precipitation[J].Journal of Sol-Gel Science and Technology,2015,76(3):592-598.
[18] KALITA S,BHARDWAJ A,BHATT A.Nanocrystalline Calcium Phosphate Ceramics in Biomedical Engineering[J].Materials Science & Engineering C,2007,27(3):441-449.
[19] HABRAKEN M,WOKLE C,JANSEN A.Ceramic Composites as Matrices and Scaffolds for Drug Delivery in Tissue Engineering[J].Advanced Drug Delivery Reviews,2007,59(4/5):234-248.
[20] ZHU W,ZHANG X,WANG D,et al.Experimental Study on the Conduction Function of Nano-hydroxyapatite Artificial Bone[J].Micro & Nano Letters,2010,5(1):19-27.
[21] 王大平,熊建义,朱伟民,等.纳米羟基磷灰石人工骨修复塌陷型胫骨平台骨折[J].中国组织工程研究,2013(51):8863-8868.